Peter Valent Selected Research

Epitopes

4/2013	A nonallergenic birch pollen allergy vaccine consisting of hepatitis PreS-fused Bet v 1 peptides focuses blocking IgG toward IgE epitopes and shifts immune responses to a tolerogenic and Th1 phenotype.
10/2008	Disruption of allergenic activity of the major grass pollen allergen Phl p 2 by reassembly as a mosaic protein.
5/2005	A hybrid molecule resembling the epitope spectrum of grass pollen for allergy vaccination.
5/2004	Generation of an allergy vaccine by disruption of the three-dimensional structure of the cross-reactive calcium-binding allergen, Phl p 7.

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Peter Valent Research Topics

Disease

80	Neoplasms (Cancer) 04/2024 - 04/2002
65	Systemic Mastocytosis 04/2024 - 01/2002
50	Leukemia 11/2023 - 11/2002
50	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2022 - 11/2002
49	Hypersensitivity (Allergy) 01/2023 - 05/2002
48	Mastocytosis 03/2024 - 02/2002
36	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2023 - 12/2002
14	Inflammation (Inflammations) 11/2020 - 07/2002
14	Seasonal Allergic Rhinitis (Hay Fever) 09/2016 - 01/2002
13	Anaphylaxis (Anaphylactic Shock) 01/2022 - 05/2007
13	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 10/2020 - 02/2006
10	Mast-Cell Leukemia (Leukemia, Mast Cell) 04/2024 - 01/2002
10	Hematologic Neoplasms (Hematological Malignancy) 07/2023 - 04/2004
9	Lymphoma (Lymphomas) 01/2018 - 01/2008
8	Eosinophilia 01/2022 - 09/2006
8	Disease Progression 01/2020 - 04/2004
7	Mast Cell Activation Disorders (Mast-Cell Disease) 03/2024 - 10/2005
7	Hereditary alpha-tryptasemia syndrome 10/2023 - 11/2020
7	Mastocytoma 03/2018 - 02/2007
6	Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic) 08/2020 - 11/2002
6	Philadelphia Chromosome 09/2017 - 12/2010
6	Pdgfra-Associated Chronic Eosinophilic Leukemia 10/2014 - 09/2006
5	Ovarian Neoplasms (Ovarian Cancer) 01/2024 - 09/2011
5	Melanoma (Melanoma, Malignant) 01/2021 - 04/2002
5	Primary Myelofibrosis (Myelosclerosis) 01/2018 - 06/2002
5	Infections 10/2017 - 02/2006
5	Aplastic Anemia (Anemia, Hypoplastic) 06/2017 - 03/2002
5	Asthma (Bronchial Asthma) 03/2017 - 05/2004
4	Anemia 08/2023 - 09/2008
4	Thrombocytopenia (Thrombopenia) 08/2023 - 04/2017
4	Blast Crisis (Blast Phase) 01/2022 - 04/2004
4	B-Cell Lymphoma (Lymphoma, B Cell) 01/2020 - 01/2017
4	Atopic Dermatitis (Atopic Eczema) 02/2016 - 07/2005
4	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 03/2014 - 01/2005
4	Myeloid Leukemia (Leukemia, Myelocytic) 05/2011 - 11/2002
3	Hypereosinophilic Syndrome (Loeffler Endocarditis) 01/2022 - 01/2005
3	Mast Cell Activation Syndrome 01/2022 - 01/2019
3	Chromosome Aberrations (Chromosome Abnormalities) 01/2021 - 05/2012
3	Pulmonary Hypertension 01/2017 - 11/2008
3	Multiple Myeloma 12/2016 - 04/2004
3	Hepatitis B 09/2016 - 06/2011

Drug/Important Bio-Agent (IBA)

43	Tryptases (Tryptase)IBA 04/2024 - 06/2002
41	Immunoglobulin E (IgE)IBA 01/2022 - 05/2002
41	AllergensIBA 02/2021 - 01/2002
28	Imatinib Mesylate (Gleevec)FDA Link 01/2016 - 07/2004
21	Tyrosine Kinase InhibitorsIBA 01/2022 - 10/2011
19	Proteins (Proteins, Gene)FDA Link 11/2023 - 11/2002
17	CytokinesIBA 01/2022 - 02/2002
17	VaccinesIBA 01/2021 - 01/2002
15	AntibodiesIBA 01/2022 - 02/2002
14	Phosphotransferases (Kinase)IBA 11/2023 - 08/2007
12	Oncogene Proteins (Oncogene Protein)IBA 01/2020 - 12/2007
12	Immunoglobulin G (IgG)IBA 12/2019 - 08/2002
11	midostaurinIBA 01/2023 - 04/2007
10	Dasatinib (BMS 354825)FDA Link 01/2017 - 08/2007
10	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2010 - 02/2002
9	nilotinib FDA Link 01/2018 - 10/2007
8	ponatinibIBA 01/2021 - 09/2013
8	AntigensIBA 10/2020 - 09/2002
7	Biomarkers (Surrogate Marker)IBA 10/2023 - 12/2002
7	Peptides (Polypeptides)IBA 09/2016 - 05/2009
6	Arthropod VenomsIBA 04/2024 - 10/2002
6	Cytarabine (Cytosar-U)FDA LinkGeneric 12/2021 - 06/2004
6	Codon (Codons)IBA 06/2019 - 01/2002
5	Surface Antigens (Surface Antigen)IBA 01/2023 - 01/2003
5	Transcription Factors (Transcription Factor)IBA 12/2021 - 10/2014
5	Messenger RNA (mRNA)IBA 03/2014 - 11/2002
5	bcr-abl Fusion ProteinsIBA 01/2013 - 12/2007
4	DNA (Deoxyribonucleic Acid)IBA 11/2023 - 11/2002
4	Histamine (Histamine Dihydrochloride)FDA Link 01/2023 - 04/2008
4	Antineoplastic Agents (Antineoplastics)IBA 01/2023 - 03/2003
4	Core Binding Factors (Core-Binding Factor)IBA 01/2021 - 01/2018
4	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2021 - 01/2008
4	ParaffinIBA 01/2020 - 04/2004
4	ruxolitinibIBA 01/2020 - 12/2016
4	Indicators and Reagents (Reagents)IBA 01/2018 - 10/2003
4	P-2 (P 2)IBA 05/2015 - 08/2002
4	Heme Oxygenase-1IBA 03/2014 - 05/2004
4	EpitopesIBA 04/2013 - 05/2004
4	Complement System Proteins (Complement)IBA 10/2010 - 07/2002
4	Peptide Hydrolases (Proteases)FDA Link 01/2008 - 07/2002
3	Tyrosine (L-Tyrosine)FDA Link 11/2023 - 10/2014
3	Cladribine FDA LinkGeneric 08/2023 - 10/2016
3	venetoclaxIBA 01/2023 - 12/2017
3	avapritinibIBA 01/2023 - 01/2022
3	Poly(ADP-ribose) Polymerase InhibitorsIBA 10/2021 - 12/2018
3	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 01/2021 - 02/2007
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 08/2020 - 02/2007
3	Protein Isoforms (Isoforms)IBA 01/2019 - 04/2002
3	dactolisibIBA 09/2017 - 09/2011
3	Membrane Proteins (Integral Membrane Proteins)IBA 09/2016 - 05/2009

Therapy/Procedure

86	Therapeutics 11/2023 - 05/2002
19	Immunotherapy 11/2020 - 01/2002
13	Drug Therapy (Chemotherapy) 01/2023 - 07/2004
8	Hematopoietic Stem Cell Transplantation 01/2017 - 12/2010
7	Precision Medicine 01/2022 - 12/2016
5	Transplantation 03/2024 - 01/2005
5	Stem Cell Transplantation 01/2021 - 07/2004
4	Cell Transplantation 03/2024 - 01/2016
3	Critical Care (Surgical Intensive Care) 01/2019 - 02/2011